Two people are dead and an estimated 120 people are injured after a pileup involving at least 100 vehicles on Thanksgiving Day on a foggy stretch on a southeast Texas highway.

Cars, minivans, pickups and tractor-trailer trucks lined the roadway badly mangled and some appeared to be totalled in a massive multi-car wreck that started at about 8:45 a.m. Thursday in the eastbound lanes of Interstate 10 near Beaumont, about 80 miles east of Houston. Several crashes followed on the interstate’s westbound lanes and southwest of Beaumont in Jefferson County.

The two fatalities happened when the vehicle they were driving in was rear-ended by an 18-wheeler. The victims were identified as 64-year-old Vincent Leggio and 60-year-old Debra Leggio, both of Pearland, Texas.

Authorities say between 80 and 120 injured victims were taken to area hospitals.

It wasn’t immediately clear how the pileup began. According to Texas Highway Patrol Trooper Stephanie Davis, preliminary reports indicated there was dense fog at the time of the crash and may be a contributing factor to the accidents.

Interstate 10 was shut down in both directions for hours. The westbound lanes reopened at 12:30 p.m.  The eastbound lanes reopened at 5 p.m.